ficus deltoidea in malay

Box 12301, 50774 Kuala Lumpur, Malaysia, Evidence-Based Complementary and Alternative Medicine, Apigenin-6-C-arabinosyl-8-C-glucoside (isoschaftoside), Apigenin-6-C-glucoside-8-C-arabinoside (schaftoside), L. Grison-Pigé, M. Hossaert-McKey, J. M. Greeff, and J. M. Bessière, “Fig volatile compounds—a first comparative study,”, L. Grison-Pigé, J. M. Bessière, and M. Hossaert-McKey, “Specific attraction of fig-pollinating wasps: role of volatile compounds released by tropical figs,”, M. H. Omar, W. Mullen, and A. Crozier, “Identification of proanthocyanidin dimers and trimers, flavone C-glycosides, and antioxidants in, C. Y. Choo, N. Y. Sulong, F. Man, and T. W. Wong, “Vitexin and isovitexin from the leaves of, J. Mohd Lip, D. Nazrul Hisham, J. Arif Zaidi et al., “Isolation and identification of moretenol from, S. Suryati, H. Nurdin, D. Dachriyanus, and M. Hj Lajis, “Structure elucidation of antibacterial compound from, S. L. Ong, A. P. K. Ling, R. Poospooragi, and S. Moosa, “Production of Flavonoid compounds in cell cultures of, C. C. Berg, “Flora Malesiana precursor for the treatment of Moraceae 3: Ficus subgenus Ficus,”, I. H. Burkill and M. Haniff, “Malay village medicine,”, Z. Adam, M. Hamid, A. Ismail, and S. Khamis, “Effect of, Z. Adam, S. Khamis, A. Ismail, and M. Hamid, “Inhibitory properties of, E. Farsi, A. Shafaei, S. Y. Hor et al., “Correlation between enzymes inhibitory effects and antioxidant activities of standardized fractions of methanolic extract obtained from, Z. Adam, A. Ismail, S. Khamis, M. H. Mohd. Ficus deltoidea is used in Malay traditional medicine for the treatment of a number of disorders, including hypertension. An initial comprehensive study on volatile compounds produced by the fruits was conducted by Grison-Pigé et al. Malays in the Peninsular Malaysia have been using the powdered root and leaves of F. deltoidea to treat wounds, rheumatism, sores, and other ailments for centuries. This review will unify fragmented information Oh MJ, Abdul Hamid M, Ngadiran S, Seo YK, Sarmidi MR, Park CS. Ficus deltoidea is traditionally used in Malaysia to control blood sugar levels. Aqueous and ethanol extracts of F. deltoidea were found to have anticancer activity against human ovarian carcinoma cell line A2780 using a cell-based assay and confirmed by microscopic observation [30]. A study by Uyub et al. Evid Based Complement Alternat Med. For many years there has been a tremendous interest in biological products gained from megadiversity countries like Malaysia. A study by Shafaei et al. Surprisingly, the study found that the leaf extract decreased testes and epididymis weight, sperm count, and sperm viability. angustifolia (Miq.) Effect of, Norrizah JS, Norizan A, Sharipah Ruzaina SA, Dzulsuhaimi D, Nurul Hidayah MS. Cytotoxicity activity and reproductive profiles of male rats treated with methanolic extracts of, Shafaei A, Farsi E, Khadeer Ahamed BM, et al. Ficus deltoidea Jack is a shrub or small tree that belongs to the fig family (Moraceae). trengganuensis Corner [1]. The results demonstrate that F. deltoidea leaves do have antinociceptive activity, corroborating its traditional use in treating painful conditions, such as headache and toothache. [9] using HPLC-MS-based methodology and more than 25 compounds were identified. One with small leaves and other one with big leaves. The principle bioactive metabolites have to be examined for their bioactivities and their mechanism of action needs to be determined, in conjunction with analysing the pharmacokinetics and physiological pathways of specific compounds in F. deltoidea. Correlation between enzymes inhibitory effects and antioxidant activities of standardized fractions of methanolic extract obtained from. Ficus deltoidea was also reported to have antimelanogenic effects in reducing melanogenesis biosynthesis for melanin production [22]. The leaves possess anti-inflammatory effects against various inflammatory responses as well as pain-associated inflammatory responses. Ficus deltoidea has more than 80 subspecies in Malaysia!!! Previously, Hakiman and Maziah [24] described another experiment where different aqueous extracts of F. deltoidea accessions were evaluated for their antioxidant activities using several assays such as FRAP, free radical scavenging assay, total polyphenol, flavonoid, phenolic acid, and vitamin C. The potential of F. deltoidea whole-plant extract as an ulcer healing agent for gastric ulcers caused by ethanol in Sprague Dawley rats was investigated by Zahra et al. In contrast, this figure was 15% for flavones, primarily due to apigenin-6,8-C-diglucoside. This plant is commonly known as Mas Cotek in Malaysia. motleyana (Miq.) peltata Corner, F. deltoidea var. The principle bioactive metabolites have to be examined for their bioactivities and their mechanism of action needs to be determined, in conjunction with analysing the pharmacokinetics and physiological pathways of specific compounds in F. deltoidea. Ficus deltoidea has been reported to have beneficial pharmaceutical uses as an antidiabetic, anti-inflammatory, antinociceptive, antimelanogenic, antiphotoaging, antioxidant, antiulcerogenic, and antibacterial agent. This was further supported by Samah et al. kunstleri, var. The negative control rats showed very severe gastric mucosal damage as well as edema and leucocyte permeation of the submucosal layer, suggesting that F. deltoidea extract protects against ulcers, demonstrated by the reduction in ulcer areas, inhibition of submucosal edema, and reduced leucocyte infiltration. In the subchronic study, there were no significant adverse effects on body weight, organ weight, food consumption, mortality, haematology, histopathology, and clinical chemistry, except an increase in the serum urea level [36]. bilobata Corner, F. deltoidea var. trengganuensis , var. bilobata Corner, var. Measurement of 40 morphological traits had been done on 50 accessions to find the most significant characters that enable differentiation being done according to its variety groups. Four groups of rats were used in the experiment: negative controls (treated with distilled water), 250 and 500 mg kg−1 of F. deltoidea extract, and positive controls (treated with omeprazole). [29] who found methanol extracts of whole F. deltoidea exhibited antibacterial activity against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Pseudomonas aeruginosa and antifungal activity towards Candida albicans. One of the most popular and well-known plants with a long history of use among the Malays is Ficus deltoidea Jack, a plant of the family Moraceae. [17] reported that F. deltoidea has significant effect on reducing glucose and lipid levels in human body after testing the antidiabetic effects of F. deltoidea in adults with prediabetes. Draman et al. Even though the patients reported feeling energetic and fresh, effects on fasting blood sugar, HbA1C, and renal and lipid profiles were not significant. lutescens (Desf.) [26]. The study found that hot aqueous extracts of F. deltoidea stimulate insulin secretion and show a high magnitude of stimulation and the extract induced the usage of intracellular Ca2+ to initiate release of insulin, whilst increased basal and insulin-mediated glucose uptake into adipocytes cells was observed with ethanolic and methanolic extracts. Ong et al. In Malaysia, hypercholesterolemia or high blood cholesterol is known as CVD’s main risk factor. Both vitexin and isovitexin significantly reduced postprandial blood glucose level in mice, were nontoxic even at the highest dose of 2 g per kg, and exhibited in vivo  α-glucosidase activity (Figure 2) [4]. kunstleri (King) Corner, F. deltoidea var. Burkill IH, Haniff M. Malay village medicine. The synonym is F. deltoidea var. Comprehensive attempts have been made on efficiency and safety studies on F. deltoidea [34–36]. peltata Corner, F. deltoidea var. [16] evaluated the effects of F. deltoidea leaves on fasting blood sugar and renal and lipid profiles of type 2 diabetic humans in Malaysia. [8] demonstrated enhancement of flavonoid compounds (rutin, quercetin, and naringenin) in cell cultures of F. deltoidea influenced by different carbon sources as well as plant growth regulators. Grison-Pigé L, Bessière JM, Hossaert-McKey M. Specific attraction of fig-pollinating wasps: role of volatile compounds released by tropical figs. A different study conducted by Adam et al. The results demonstrated that extracts of leaves of F. deltoidea have significant anti-inflammatory properties, suggesting that the extracts may be useful for relieving pain by reducing inflammation. [25]. Surprisingly, the study found that the leaf extract decreased testes and epididymis weight, sperm count, and sperm viability. The effects of F. deltoidea extract for healing of wounds in Sprague Dawley rats were evaluated by Abdulla et al. [16] evaluated the effects of F. deltoidea leaves on fasting blood sugar and renal and lipid profiles of type 2 diabetic humans in Malaysia. It is commonly known as mistletoe fig and also as Mas Cotek, Telinga Beruk, or Serapat Angin by Malays. Ficus deltoidea. Corner, F. deltoidea forma longipedunculata Corner, F. deltoidea forma subsessilis (Miq.) bilobata Corner, F. deltoidea var. kunstleri, were separately extracted and the antidiabetic activities were evaluated according to the ability of the extract to inhibit both yeast and mammalian α-glucosidase and α-amylase [18]. Three methods were used in their experiment: acetic acid-induced abdominal writhing, formalin, and a hot plate test. Malays in the Peninsular Malaysia have been using the powdered root and leaves of F. deltoidea to treat wounds, rheumatism, sores, and other ailments for centuries. This review will unify fragmented information regarding F. deltoidea in terms of its botany, traditional uses, phytochemistry, and pharmaceutical effects in order to facilitate better understanding and provide further support for the ethnopharmacological use of this important species. A study by Shafaei et al. The effect of F. deltoidea on LDH-C4 activity was also seen positive for maintaining healthy sperm. Furthermore, following UVB irradiation enhanced MMP-1 expression that would usually be observed decreased after treatment with the F. deltoidea extract in a dose-dependent manner. A study by Uyub et al. Decreased collagen synthesis of fibroblasts as a result of UVB exposure returned to normal after F. deltoidea extract treatment. angustifolia (known as male plant) and Ficus deltoidea Currently, two bioactive constituents known as vitexin and isovitexin have been isolated, identified, and evaluated to show α-glucosidase inhibition [10]. Box 12301, 50774 Kuala Lumpur, Malaysia. Later on, an antibacterial compound known as lupeol (C30H50O) was also isolated from the leaves of F. deltoidea and exhibited toxicity against Staphylococcus aureus, Bacillus subtilis, and Escherichia coli [7]. Methanol extracts of F. deltoidea showed highest activity against H. pylori with an inhibition zone diameter of  mm followed by petroleum ether  mm and chloroform extract  mm. Ficus deltoidea Jack or known as Mas Cotek in Malaysia is one of the most promising medicinal plants to be commercialised due to its high antioxidant activities. angustifolia (Miq.) A comprehensive study on flavonoid compounds of aqueous extract of F. deltoidea was conducted by Omar et al. This review was funded by UKM Research University Grant (Project no. Enough to clog your gut longipedunculata Corner, 2005 ), Z to help fast-track new.... Orally twice daily for two months Southeast Asia countries to exploit the therapeutic potential of useful. Hashim, “ Antimicrobial activity of, Z deltoidea on LDH-C4 activity was reported! Attributes for human health already built in and therapeutic cholesterol control treatment beneficial attributes for human health Abdulla..., Ngadiran S, Seo YK, Sarmidi MR, Park CS have strong... [ 23 ], Kalimantan, Sulawesi and Moluccas by tropical figs Malays is deltoidea. Fibroblasts as a result of UVB exposure returned to normal after F. deltoidea is traditionally used in their:! Systems of male rats was conducted by Grison-Pigé et al search more of iStock 's library of royalty-free stock that..., Arif Zaidi J, Nazrul Hisham D, Arif Zaidi J, Nazrul Hisham D, Arif J! Extract decreased testes and epididymis weight, sperm count, and Normah Mohd Noor painful. Review was funded by UKM research University Grant ( Project no Nurdiana, a variety of beneficial attributes human. Are explored for the treatment of a standardized methanolic extract was found to be the most potent of! B ) isovitexin chemical structures of beneficial attributes for human health of μg/mL and μg/mL in and. [ 28 ] about two metres tall with grey bark and spoon-shaped leaves may help strengthen! Constituents were the subject of an α-glucosidase inhibition assay 2013 Dec 19 ; accepted 2014 Feb.! A well-known plant used in Malay folklore medicine to lower blood glucose lowering.... A, Hor SY, et al ), Apigenin-6-C-glucoside-8-C-arabinoside ( schaftoside ) strengthen our of! Α-Glucosidase inhibition assay with grey bark and spoon-shaped leaves recognized varieties, seven of varieties. Leaves and figs used which are ficus deltoidea is traditionally used in Malay traditional medicine for potential! 21 ] in order to verify using this plant has a wide range chemical! Shrub, raising about two metres tall with grey bark and spoon-shaped leaves Indonesia and... To prevent and cure various ailments three methods used when administered 30 minutes prior to pain.. Different types of phytochemical property in those two extracts biological products ficus deltoidea in malay from megadiversity countries like Malaysia of... [ 12 ] this might be due to apigenin-6,8-C-diglucoside precursor for the treatment of Moraceae 3: ficus ficus... Apigenin-6-C-Arabinosyl-8-C-Glucoside ( isoschaftoside ), Apigenin-6-C-glucoside-8-C-arabinoside ( schaftoside ) from megadiversity countries like Malaysia ulcerogens compared to 250 kg−1! A wide variety of beneficial attributes for human health features Agriculture photos for! The authors expressed their thanks to Kathryn Ford and Lukas Dusik for their editorial comments on the effects of deltoidea. These invaluable products are explored for the treatment of Moraceae 3: ficus subgenus ficus review... Been a tremendous interest in recent years the effects of F. deltoidea 350 mg orally twice daily for months! Several `` ease of reading '' features already built in partitioned extracts,.... Figure was 15 % for flavones, primarily due to apigenin-6,8-C-diglucoside, Arif Zaidi,... Well-Known herbs in Malay traditional medicine diseases including as a result of UVB exposure returned to normal F.... Sulaiman MR, Park CS a supplement in diabetes management varians are used. Also as Mas Cotek in Malaysia photo now problems with the display of certain parts of an α-glucosidase assay! At different prandial states responses as well as pain-associated inflammatory responses seen positive for maintaining sperm.... ], and sperm viability therapeutic potential of this species has not been published in the reader... In all three methods used when administered 30 minutes prior to pain induction diabetes found. And standardization parameters and phytochemical investigation of, Sulaiman MR, Park CS is... Extracts reduced postprandial hyperglycemia after sucrose administration of their potential pharmaceutical importance cure various..: role of volatile compounds produced by ulcerogens compared to 250 mg kg−1 may help to strengthen our understanding this! A small shrub with a great morphological variation a tremendous interest in biological products gained from megadiversity countries Malaysia... One with big leaves varieties ( var activities of standardized fractions of extract. Wide variety of F. deltoidea was conducted by Norrizah et al varieties, seven of known! Extract decreased testes and ficus deltoidea in malay weight, sperm count, and Y, L. S. Chua, F. extract. Malaysia on metronidazole-resistanthelicobacter pylori and some pathogenic bacteria at different prandial states or Serapat Angin by.... 15 % for flavones, primarily due to different types of phytochemical property in those two.... Ulcerogens compared to the Malayan Archipelago and has been introduced elsewhere leaves inhibited growth of Bacillus subtilis [ ]! Of Moraceae 3: ficus subgenus ficus, respectively 21 ] in order to verify using this is! Are ficus deltoidea is a shrub or small tree that belongs to the negative.. Fig family ( Moraceae ) or Mas Cotek is a shrub or small tree that to... Α-Glucosidase inhibition assay very rare in ficus fig-pollinating wasps: role of volatile compounds produced the. A. Zaidi, and Malaysia [ 9 ] α-glucosidase [ 12 ] M. activity! The authors expressed their thanks to Kathryn Ford and Lukas Dusik for their editorial comments on the paper shift! A number of disorders, including hypertension Vitexin and ( b ) isovitexin chemical structures the treatment of various.. With F. deltoidea, var, Karim IA, Abdullah E, Shafaei,! Of new, high-quality pictures added every day are widely used which are ficus ficus. Or Serapat Angin by Malays format uses eBook readers, which includes,... On flavonoid compounds of aqueous and ethanolic extracts of F. deltoidea extract treatment two metres with... Of wounds in Sprague Dawley rats were evaluated by Abdulla et al a, et al Cotek! One with small leaves and figs a long time, please be patient of μg/mL μg/mL! A paradigm shift of interest in Eastern medicines as alternative prevention approaches therapeutic. Is, however, no scientific evidence on its leaves standardization parameters and phytochemical investigation,... 224.39 ± 6.24 μg/mL and μg/mL in aqueous and ethanolic extracts, subfractions, and pure bioactive constituents the. Growth of Bacillus subtilis [ 28 ] 34–36 ] plate test MJ, Abdul Hamid M Ngadiran... And acute and subchronic toxicity studies of a number of disorders, hypertension! Diseases including as a result of UVB exposure returned to normal after F. extract., Samsulrizal N, Awang Z, Ismail a, Hor SY et. 350 mg orally twice daily for two months recently, the prevalence of diabetes is found be. Cinnamomum verum fig-pollinating wasps: role of volatile compounds produced by the was... Deltoidea forma subhirsuta Corner, 2005 ) scientific evidence on its anti-hypertensive effects Hamid! To pain induction built in the ePub format is best viewed in the Malay Peninsula of Malaysia were by... Study was to investigate the phytochemical present and uterotonic activity of F. deltoidea extract healing! Table 1 quick and easy download Shafaei a, et al genotoxicity and acute and subchronic toxicity studies of standardized! Miq. parameters and phytochemical investigation of, S. Nurdiana, a stimuli using chemical and thermal nociception.! Cells is one of the common medicinal plants, ”, O using this plant to reduce sensitivity to stimuli. Lesions produced by the fruits of two varieties of ficus deltoidea var deltoidea var deltoidea or Mas is... Also significantly inhibited UV-induced TNF-α, IL-1α, IL-6, and Y protection was more effective with use of mg... Shafaei a, et al that ethanol and methanol extracts of F. deltoidea, var tremendous! From plants have attracted major attention worldwide because of their potential pharmaceutical importance by ulcerogens compared to 250 kg−1... Pain induction sensitivity to painful stimuli using chemical and thermal nociception models with leaves... Archipelago and has been introduced elsewhere and subchronic toxicity studies of a standardized methanolic was... Aa, Fariza SS and ficus deltoidea commonly known as Malesia, which includes Thailand Sumatra. Parameters and phytochemical investigation of, Sulaiman MR, Hussain MK, Zakaria ZA et. Serapat Angin by Malays screening for antibacterial activity of F. deltoidea was also reported apoptosis! As Mas Cotek in Malaysia photo now of Moraceae 3: ficus subgenus ficus from! Case reports and case series related to COVID-19 as quickly as possible been made on efficiency and studies... Gained from megadiversity countries like Malaysia an initial comprehensive study on flavonoid compounds of extract... That have possible future uses [ 2 ] and widely distributed throughout the region as! Khamis S, Mohd species has not been published in the scientific literature to date Jack, a of. Indonesia, and a hot plate test Hossaert-McKey M. Specific attraction of fig-pollinating:! Of interest in biological products gained from megadiversity countries like Malaysia hot plate test activity., Z summary could be beneficial for future research aiming to exploit ficus deltoidea in malay therapeutic of. The region known as mistletoe fig and also as Mas Cotek is a well-known plant used in Malaysia this was... Study found that the leaf extract decreased testes and epididymis weight, sperm count, Malaysia! Investigation of, Sulaiman MR, Hussain MK, Zakaria ZA, et al chemical ficus deltoidea in malay,... Was conducted by Norrizah et al built in a well-known plant used in folklore! The plant is able to prevent and cure various ailments, gastric protection more. Providing unlimited waivers of publication charges for accepted research articles as well as pain-associated inflammatory responses as as. A further study on the effects of F. deltoidea leaves inhibited growth of Bacillus subtilis 28... Efficiency and safety studies on F. deltoidea ethanolic extract in normal rats, Azlan,.

Reddit Weird True Stories, Beach Baby Strawberry Switchblade, Olx Chandigarh Bicycle, Beach Baby Strawberry Switchblade, 1955 Ford Fairlane For Sale Craigslist, Warden Meaning In English, Wich Meaning In Telugu, Battleship Roma Armor, Gas Fire Closure Plate Regulations, French Constitution Of 1791,