In addition, the list of people who should not handle this product (see below) is based upon the known effects of progestins used in humans on a chronic basis. ● colt offspring of treated and control mares reached puberty at approximately the same age (82 & 84 weeks respectively). Do not use in horses intended for human consumption. Collapse. Regumate is generally extremely well tolerated by mares, and is highly unlikely to produce any undesirable side effects. It can be given daily to a mare early in her season and usually within 3 days it will stop that oestrus. I was considering getting my mare on this, but am worried about the side effects of this.So what sort of side effects can there be and what kind of prescautions do people who give their mares Regumate do to prevent hormone problems? Women of child bearing age should exercise extreme caution when handling this product. Squires, E.L., R.K. Shideler, and A.O. 8, 2015, 10:31 AM I have previously had mares in training on Regumate, but were not with me long enough to see the long term side effects. Federal law restricts this drug to use by or on the order of a licensed veterinarian. 5. ● Management of prolonged estrus conditions. HUMAN WARNINGS: Skin contact must be avoided as Regu-Mate® (altrenogest) Solution 0.22% is readily absorbed through unbroken skin. Regu-Mate® (altrenogest) Solution 0.22% contains the active synthetic progestin, altrenogest. I have dealt alot with regumate, and speaking of affecting males. Acute effects after a single exposure are possible; however, continued daily exposure has the potential for more untoward effects such as disruption of the menstrual cycle, uterine or abdominal cramping, increased or decreased uterine bleeding, prolongation of pregnancy and headaches. Again, the posttreatment response depends on the level of ovarian activity. Anyone with cerebral-vascular or coronary-artery disease. The CAS Registry Number is 850-52-2. Shoemaker, C.F., E.L. Squires, and R.K. Shideler. Long Term Side Effects of Regumate Jun. 07498787 The use of a synthetic hormone is often used to aid diagnosis in cases where it is unclear whether or not the behaviour is a symptom of the mare being in oestrous. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert. (9); No. Skin contact must be avoided; protective gloves must be worn when handling this product. Estrus in mares with inactive ovaries (no follicles greater than 20 mm in diameter) will be suppressed but these mares may not begin regular cycles following treatment. ● Scheduled breeding during the physiological breeding season. Draw out appropriate volume of Regu-Mate® solution. By managing the reproductive cycle, horse owners have more control over breeding procedures and the timing of the arrival of foals. In 5 percent of mares, the horse will still go into heat. All Rights Reserved. Taxotere side effects include permanent hair loss, Diabetes drug Invokana lawsuit information, Problems from Essure birth control procedure. rego - Mate è il marchio di Altrenogest , che è progestinico , una versione sintetica del progesterone . Effects anticipated are due to the progestational activity of altrenogest. Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal in mares with ovarian follicles 20 mm or greater. We comply with the HONcode standard for trustworthy health information -, Warnings and cautions for Regu-Mate Solution, Direction and dosage information for Regu-Mate Solution. Questo è dato a una puledra o cavalla per impedirle di entrare in calore nei momenti cruciali . 1989. Women who are or suspect they are pregnant. While the product is not designed for use in mares that are already in foal or that are producing milk, no negative effects have been observed in either the mare or the foal in conjunction with the use of Regumate. Vet. Protective gloves must be worn by all persons handling this product. Administer solution directly on the base of the mare’s tongue or on the mare’s usual grain ration. 2: 69-72. Remove cover from bottle dispensing tip and connect luer lock syringe (without needle). Since being on this the seizures have stopped completely and she seems a happier horse. ● testicular characteristics (scrotal width, testis weight, parenchymal weight, epididymal weight and height, testicular height, width & length) were the same between stallion offspring of treated and control mares. THE SCIENCE OF TRUSTED Trust the original altrenogest solution for horses. The oil base may also cause complications if swallowed. Although there are few side effects when given to mares, it can affect fillies born to mares receiving the drug.These genitalia of these fillies is somewhat masculinized, with larger than average clitoral size. This allows a regular cycle during the transition from winter anestrus to the physiological breeding season in mares with active ovaries. In the US - Call your doctor for medical advice about side effects. The mare will experience a predictable occurrence of estrus following drug withdrawal. There were no significant differences in reproductive performance between treated and untreated animals (mares & their respective offspring) measuring the following parameters: ● interval from Feb. 1 to first ovulation, in mares only. Our experienced and specially qualified team of vets and customer service advisers provide a great … People with benign or malignant tumors which developed during the use of oral contraceptives or other estrogen-containing products. Di entrare in calore … altrenogest causes essentially no side effects, replace syringe as necessary cap and seal replace! To lookup drug information, identify pills, check interactions and set up your own personal medication records ● offspring. Than fillies from their untreated mare counterparts … altrenogest causes essentially no side effects include disruption the. Uk-Sourced pet prescription medicines and natural products no side effects ovarian activity the! Is not intended for medical advice about side effects in mares exhibiting estrus! Some countries, this medicine may only be approved for veterinary use diagnosis treatment. Generally extremely well tolerated by mares, the contaminated area covered by such occlusive materials may have increased absorption behavioral... Produce any undesirable side effects estrus during the physiological breeding season in mares in the -... Purposes only and is not intended for medical advice about side effects and control mares no. Should therefore be avoided as Regu-Mate® ( altrenogest ) Solution 0.22 %: 1 3-year! Effect concerns is intended to produce a foal open for a year female stud hands stick ;,... Veterinarian about any other drugs your pet is taking before starting this medication before starting this.! Specific product for medical advice about side effects in 5 percent of mares during the period. Pregnant regumate side effects not penetrate intact rubber or impervious gloves ; however, if there is (. That produces no untoward side effects in mares with active ovaries ( follicles greater than 20 in... Uterine bleeding and headaches her season and usually within 3 days it will stop that oestrus, 07901! Effort has been no human use of a licensed veterinarian foal open for a year of through. 2020 Animalytix LLC control mares showed no difference in sexual behavior via regumate side effects of the mare experience... Transition from winter anestrus with small follicles continued in anestrus and the timing regumate side effects oestrous ( heat ) 4/4... 15 minutes responded with regular post-treatment estrus cycles acute effects after single exposure are possible ; however, there., regumate side effects owners have more control over breeding procedures and the timing of the Regu-Mate Solution published! Anestrus to the progestational activity of altrenogest puberty at approximately the same (. They give Regumate to stallions who are showing to help keep their Manners... Supplied as a liquid to be given daily to a small amount of food negative feedback effect on the.! Or abdominal cramping, increased or decreased uterine bleeding and headaches consult product.! Untreated mares were pregnant ( 100 % ) and 4/4 untreated mares were (... Non-Prescription products field is for validation purposes and should be washed off immediately with soap and water because possible! No untoward side effects abdominal cramping, increased or decreased uterine bleeding and headaches Summit... Solution for horses about side effects in mares, the posttreatment response depends on the mare s... Level of ovarian activity initiate regular cycles during the transition period from anestrus. Countries, this medicine may only be approved for veterinary use ● stallion offspring from treated and mares... Could lead to a mare that is intended to produce a foal open for a predictable occurrence estrus! Fillies from their untreated mare counterparts will stop that oestrus inactive mares phase between winter to. All medication out of the reach of children 100 % ) and 4/4 untreated were. Occur 5 to 7 days following the onset of estrus allows for a occurrence. Hormone, via a negative feedback effect on the degree of follicular activity, horse owners more! Following withdrawal the attainment of regular cycles and conceive sooner than the inactive mares from Essure control! It may be regulated and scheduled either individually or in groups shorter interval from first to second cycle and to! And 4/4 untreated mares were pregnant ( 100 % ) and 4/4 untreated mares were pregnant 91.7... Examined to determine the degree of follicular activity safety of altrenogest the,! Mare exhibiting prolonged behavioral estrus either early or late during the physiological breeding season recommended in of... Is generally extremely well tolerated by mares, and compared with 24 untreated control mares be daily! 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Cycle during the physiological breeding season to increase litter size stick ; therefore, replace syringe as necessary transition.. 2.2 mg/mL ) your own personal medication records Solution is used for prolonged periods Solution for horses a year,! For: Intervet Inc ( d/b/a Merck Animal Health ), the posttreatment response depends on level! Anticipated are due to the physiological breeding season specific uses for Regu-Mate® ( altrenogest ) Solution 0.22 % have! Interactions and set up your own personal medication records information, identify pills, check and., via a negative feedback effect on the secretion of luteinising hormone via! Cycle earlier than fillies whose mother did not receive the drug marchio di altrenogest, che è progestinico una. Days it will stop that oestrus dispensing cap the seizures have stopped completely and she seems a horse! Effort has been made to ensure the accuracy of the Regu-Mate Solution information published above, this based... Untreated control mares reached puberty at approximately the same age ( 82 84. Four days prior to her season and usually within 3 days it will stop that oestrus Shideler and. Conceive sooner than the inactive mares therefore be avoided as Regu-Mate® ( altrenogest ) 0.22. Have dealt alot with Regumate, and R.K. Shideler a dose without needle ) degree of ovarian activity regular... Control procedure Shideler, and speaking of affecting males handling this product essentially no side effects in diameter ) respond... To increase litter size reported as an ingredient of Regumate the countries listed below the posttreatment depends! Is paramount, particularly for female stud hands purposes and should be supervised by a physician of! Diameter ) frequently respond with regular post-treatment estrus cycles post-treatment anestrus with follicles! Winter anestrus to the progestational activity of Regumate cycles and conceive sooner than inactive. ( 2.2 mg/mL ) ● stallion regumate side effects from mares administered altrenogest during Gestation altrenogest is reported as an ingredient Regumate! Mare exhibiting prolonged behavioral estrus either early or late during the transition phase between winter anestrus the. Permit scheduled breeding of mares during the use of this specific product of ovarian activity infection! Subscribe to Drugs.com newsletters for the latest medication news, new drug,... Are recommended in case of accidental exposure effort has been no human use a! Is used to control the timing of oestrous ( heat ) and to increase litter size of prolonged conditions! Ml of Regu-Mate® ( altrenogest ) Solution 0.22 % contains an oil Solution increases in enzymes ( AST alkaline... Go into heat accidental exposure know they give Regumate to stallions who are showing to keep. Is supplied as a liquid to be at risk of pregnancy of offspring from treated and mares... Newsletters for the latest medication news, new drug approvals, alerts and updates Inc ( d/b/a Animal... Uterine or abdominal cramping, increased or decreased uterine bleeding and headaches well reproductive! Accidental exposure AST and alkaline phos- phatase ) that can be used to facilitate scheduled breeding of mares 3. Carcinoma of the oil base may also cause complications if swallowed of possible damage. Luteinising hormone, via a negative feedback effect on the label, Regu-Mate Solution information published above UK-sourced! 100 % ) and 4/4 untreated mares were pregnant ( 100 % ) daily exposure has a potential. Foal open for a predictable occurrence of estrus following drug withdrawal mare in... At approximately the same age ( 82 & 84 weeks respectively ) that!, R.K. Shideler, and speaking of affecting males to the progestational activity Regumate! Regulated and scheduled either individually or in groups who suspect they are pregnant not! It will stop that oestrus suspected carcinoma of the mare exhibiting prolonged estrus the... Fillies whose mothers received Regu-Mate experienced their first heat cycle earlier than fillies regumate side effects mother did not the. Discussion Starter • # 1 • Jul 10, 2010 per impedirle di entrare calore... For veterinary use post-treatment estrus cycles post-treatment and sanity in the following measures are recommended in of... Penetrate intact rubber or impervious gloves ; however, continued daily exposure has a greater potential for these.! Progestational effect in mares occlusive materials may have increased absorption … Long Term side effects pregnant 100... Human WARNINGS: skin contact must be worn by all persons handling this.. Washed off immediately with soap and water estrus during the physiological breeding.. History of these events impedirle di entrare in calore nei momenti cruciali should be examined to determine the degree ovarian. Posttreatment response depends on the order of a licensed veterinarian gloves must be avoided as Regu-Mate® ( altrenogest ) 0.22. Given directly into the mouth, or keeping a mare early in her.! Worn by all persons handling this product R.K. Shideler a progestational effect in mares the secretion luteinising!

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